Serum IgE Induced Airway Smooth Muscle Cell Remodeling Is Independent of Allergens and Is Prevented by Omalizumab

BACKGROUND: Airway wall remodeling in allergic asthma is reduced after treatment with humanized anti-IgE-antibodies. We reported earlier that purified IgE, without the presence of allergens, is sufficient to induce airway wall remodeling due to airway smooth muscle cell (ASMC) activity deposing extr...

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Detalles Bibliográficos
Autores principales: Roth, Michael, Zhao, Feng, Zhong, Jun, Lardinois, Didier, Tamm, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557956/
https://www.ncbi.nlm.nih.gov/pubmed/26332463
http://dx.doi.org/10.1371/journal.pone.0136549

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557956/
https://www.ncbi.nlm.nih.gov/pubmed/26332463
http://dx.doi.org/10.1371/journal.pone.0136549

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