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Altered FGF Signaling Pathways Impair Cell Proliferation and Elevation of Palate Shelves
In palatogenesis, palatal shelves are patterned along the mediolateral axis as well as the anteroposterior axis before the onset of palatal fusion. Fgf10 specifically expressed in lateral mesenchyme of palate maintains Shh transcription in lateral epithelium, while Fgf7 activated in medial mesenchym...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558018/ https://www.ncbi.nlm.nih.gov/pubmed/26332583 http://dx.doi.org/10.1371/journal.pone.0136951 |