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Allele-Selective Transcriptome Recruitment to Polysomes Primed for Translation: Protein-Coding and Noncoding RNAs, and RNA Isoforms

mRNA translation into proteins is highly regulated, but the role of mRNA isoforms, noncoding RNAs (ncRNAs), and genetic variants remains poorly understood. mRNA levels on polysomes have been shown to correlate well with expressed protein levels, pointing to polysomal loading as a critical factor. To...

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Detalles Bibliográficos
Autores principales: Mascarenhas, Roshan, Pietrzak, Maciej, Smith, Ryan M., Webb, Amy, Wang, Danxin, Papp, Audrey C., Pinsonneault, Julia K., Seweryn, Michal, Rempala, Grzegorz, Sadee, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558023/
https://www.ncbi.nlm.nih.gov/pubmed/26331722
http://dx.doi.org/10.1371/journal.pone.0136798

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