Three Different Pathways Prevent Chromosome Segregation in the Presence of DNA Damage or Replication Stress in Budding Yeast

A surveillance mechanism, the S phase checkpoint, blocks progression into mitosis in response to DNA damage and replication stress. Segregation of damaged or incompletely replicated chromosomes results in genomic instability. In humans, the S phase checkpoint has been shown to constitute an anti-can...

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Detalles Bibliográficos
Autores principales: Palou, Gloria, Palou, Roger, Zeng, Fanli, Vashisht, Ajay A., Wohlschlegel, James A., Quintana, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558037/
https://www.ncbi.nlm.nih.gov/pubmed/26332045
http://dx.doi.org/10.1371/journal.pgen.1005468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558037/
https://www.ncbi.nlm.nih.gov/pubmed/26332045
http://dx.doi.org/10.1371/journal.pgen.1005468

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