AMP-activated kinase (AMPK) regulates activity of HER2 and EGFR in breast cancer

AMP-activated Protein Kinase (AMPK) activity retards growth of many types of cancers. Investigating effects of AMPK activation on breast cancer cell signaling and survival, we found that breast cancer cell lines with amplification and over-expression of HER2 or EGFR are 2- to 5-fold more sensitive t...

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Detalles Bibliográficos
Autores principales: Jhaveri, Teraneh Z., Woo, Juhyung, Shang, Xiaobin, Park, Ben Ho, Gabrielson, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558113/
https://www.ncbi.nlm.nih.gov/pubmed/26143491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558113/
https://www.ncbi.nlm.nih.gov/pubmed/26143491

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