Cargando…

AMP-activated kinase (AMPK) regulates activity of HER2 and EGFR in breast cancer

AMP-activated Protein Kinase (AMPK) activity retards growth of many types of cancers. Investigating effects of AMPK activation on breast cancer cell signaling and survival, we found that breast cancer cell lines with amplification and over-expression of HER2 or EGFR are 2- to 5-fold more sensitive t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jhaveri, Teraneh Z., Woo, Juhyung, Shang, Xiaobin, Park, Ben Ho, Gabrielson, Edward
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Priority Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558113/ https://www.ncbi.nlm.nih.gov/pubmed/26143491

Ejemplares similares

AMP-activated protein kinase-dependent nuclear localization of glyceraldehyde 3-phosphate dehydrogenase in senescent human diploid fibroblasts
por: Sohn, Jee Young, et al.
Publicado: (2022)

AMP-activated protein kinase is dispensable for maintaining ATP levels and for survival following inhibition of glycolysis, but promotes tumour engraftment of Ras-transformed fibroblasts
por: Pelletier, Joffrey, et al.
Publicado: (2015)

AMP-Activated Protein Kinase (AMPK) and Energy-Sensing in the Brain
por: Ramamurthy, Santosh, et al.
Publicado: (2012)

Roles of AMP-Activated Protein Kinase (AMPK) in Mammalian Reproduction
por: Yang, Weina, et al.
Publicado: (2020)

Activation of the AMP-Activated Protein Kinase (AMPK) by Nitrated Lipids in Endothelial Cells
por: Wu, Yong, et al.
Publicado: (2012)

Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly
por: Hinchy, Elizabeth C., et al.
Publicado: (2018)

Activation of AMP-activated protein kinase (AMPK) through inhibiting interaction with prohibitins
por: Kanagaki, Shuhei, et al.
Publicado: (2023)

AMP-Activated Kinase AMPK Is Expressed in Boar Spermatozoa and Regulates Motility
por: Hurtado de Llera, Ana, et al.
Publicado: (2012)

Perspectives of the AMP-activated kinase (AMPK) signalling pathway in thyroid cancer
por: Andrade, Bruno Moulin, et al.
Publicado: (2014)

AMP-Activated Protein Kinase (AMPK)-Dependent Regulation of Renal Transport
por: Glosse, Philipp, et al.
Publicado: (2018)

Sumoylation of AMPKβ2 subunit enhances AMP-activated protein kinase activity
por: Rubio, Teresa, et al.
Publicado: (2013)

Retraction: Activation of the AMP-Activated Protein Kinase (AMPK) by Nitrated Lipids in Endothelial Cells
Publicado: (2020)

Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells
por: Zhang, Chuanzhao, et al.
Publicado: (2016)

Deconvoluting AMP-activated protein kinase (AMPK) adenine nucleotide binding and sensing
por: Gu, Xin, et al.
Publicado: (2017)

RN765C, a low affinity EGFR antibody drug conjugate with potent anti-tumor activity in preclinical solid tumor models
por: Wong, Oi Kwan, et al.
Publicado: (2018)

Fyn phosphorylates AMPK to inhibit AMPK activity and AMP-dependent activation of autophagy
por: Yamada, Eijiro, et al.
Publicado: (2016)

Metformin suppresses adipogenesis through both AMP-activated protein kinase (AMPK)-dependent and AMPK-independent mechanisms
por: Chen, Suet Ching, et al.
Publicado: (2017)

Homogenous Fluorescent Assays for Characterizing Small-Molecule Activators of AMP-Activated Protein Kinase (AMPK)
por: Reichling, Laurie J, et al.
Publicado: (2008)

Cordycepin activates AMP-activated protein kinase (AMPK) via interaction with the γ1 subunit
por: Wu, Chongming, et al.
Publicado: (2014)

A Highly Sensitive Non-Radioactive Activity Assay for AMP-Activated Protein Kinase (AMPK)
por: Yan, Yan, et al.
Publicado: (2017)

A High Throughput Assay for Discovery of Small Molecules that Bind AMP-activated Protein Kinase (AMPK)
por: Sinnett, Sarah E, et al.
Publicado: (2013)

Serum HER2 levels are increased in cats with mammary carcinomas and predict tissue HER2 status
por: Soares, Maria, et al.
Publicado: (2016)

Down-regulation of AMPK signaling pathway rescues hearing loss in TFB1 transgenic mice and delays age-related hearing loss
por: Zhao, Jingjing, et al.
Publicado: (2020)

Role of AMP-Activated Protein Kinase (AMPK) in Smoking-Induced Lung Inflammation and Emphysema
por: Lee, Jae Seung, et al.
Publicado: (2015)

Discovery and translation of a target engagement marker for AMP-activated protein kinase (AMPK)
por: Grempler, Rolf, et al.
Publicado: (2018)

Involvement of 5′AMP-Activated Protein Kinase (AMPK) in the Effects of Resveratrol on Liver Steatosis
por: Trepiana, Jenifer, et al.
Publicado: (2018)

Comparison of SARS-CoV-2 RT-PCR on a high-throughput molecular diagnostic platform and the cobas SARS-CoV-2 test for the diagnostic of COVID-19 on various clinical samples
por: Opota, Onya, et al.
Publicado: (2020)

Fasting potentiates the anticancer activity of tyrosine kinase inhibitors by strengthening MAPK signaling inhibition
por: Caffa, Irene, et al.
Publicado: (2015)

The relationship of NM23 (NME) metastasis suppressor histidine phosphorylation to its nucleoside diphosphate kinase, histidine protein kinase and motility suppression activities
por: Khan, Imran, et al.
Publicado: (2017)

Lymphocytes Accelerate Epithelial Tight Junction Assembly: Role of AMP-Activated Protein Kinase (AMPK)
por: Tang, Xiao Xiao, et al.
Publicado: (2010)

Isolation of AMP-activated protein kinase (AMPK) alleles required for neuronal maintenance in Drosophila melanogaster
por: Swick, Lance L., et al.
Publicado: (2013)

Epigenetic suppression of EGFR signaling in G-CIMP+ glioblastomas
por: Li, Jie, et al.
Publicado: (2014)

Suppression of Her2/Neu mammary tumor development in mda-7/IL-24 transgenic mice
por: Li, You-Jun, et al.
Publicado: (2015)

Isoquercitrin activates the AMP–activated protein kinase (AMPK) signal pathway in rat H4IIE cells
por: Zhou, Jingxin, et al.
Publicado: (2014)

Hypoxia promotes drug resistance in osteosarcoma cells via activating AMP-activated protein kinase (AMPK) signaling
por: Zhao, Changfu, et al.
Publicado: (2016)

Calcium-Oxidant Signaling Network Regulates AMP-activated Protein Kinase (AMPK) Activation upon Matrix Deprivation
por: Sundararaman, Ananthalakshmy, et al.
Publicado: (2016)

Kahweol inhibits lipid accumulation and induces Glucose-uptake through activation of AMP-activated protein kinase (AMPK)
por: Baek, Jung-Hwan, et al.
Publicado: (2017)

AMP-Activated Protein (AMPK) in Pathophysiology of Pregnancy Complications
por: Kumagai, Asako, et al.
Publicado: (2018)

AMP-independent activator of AMPK for treatment of mitochondrial disorders
por: Moore, Tereza, et al.
Publicado: (2020)

EGFR-targeted therapy results in dramatic early lung tumor regression accompanied by imaging response and immune infiltration in EGFR mutant transgenic mouse models
por: Venugopalan, Abhilash, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_slo7gsb4n55rtudq5ajbs593ri