RNA nanoparticle as a vector for targeted siRNA delivery into glioblastoma mouse model

Systemic siRNA administration to target and treat glioblastoma, one of the most deadly cancers, requires robust and efficient delivery platform without immunogenicity. Here we report newly emerged multivalent naked RNA nanoparticle (RNP) based on pRNA 3-way-junction (3WJ) from bacteriophage phi29 to...

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Detalles Bibliográficos
Autores principales: Lee, Tae Jin, Haque, Farzin, Shu, Dan, Yoo, Ji Young, Li, Hui, Yokel, Robert A., Horbinski, Craig, Kim, Tae Hyong, Kim, Sung-Hak, Kwon, Chang-Hyuk, Nakano, Ichiro, Kaur, Balveen, Guo, Peixuan, Croce, Carlo M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558114/
https://www.ncbi.nlm.nih.gov/pubmed/25885522

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