Accelerated hepatocellular carcinoma development in CUL4B transgenic mice

Cullin 4B (CUL4B) is a component of the Cullin 4B-Ring E3 ligase (CRL4B) complex that functions in proteolysis and in epigenetic regulation. CUL4B possesses tumor-promoting properties and is markedly upregulated in many types of human cancers. To determine the role of CUL4B in liver tumorigenesis, w...

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Detalles Bibliográficos
Autores principales: Yuan, Jupeng, Jiang, Baichun, Zhang, Aizhen, Qian, Yanyan, Tan, Haining, Gao, Jiangang, Shao, Changshun, Gong, Yaoqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558146/
https://www.ncbi.nlm.nih.gov/pubmed/25945838

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