Cargando…
A small molecule inhibitor of atypical protein kinase C signaling inhibits pancreatic cancer cell transformed growth and invasion
Pancreatic cancer is highly resistant to current chemotherapies. Identification of the critical signaling pathways that mediate pancreatic cancer transformed growth is necessary for the development of more effective therapeutic treatments. Recently, we demonstrated that protein kinase C iota (PKCι)...
Autores principales: | Butler, Amanda M., Scotti Buzhardt, Michele L., Erdogan, Eda, Li, Shuhua, Inman, Kristin S., Fields, Alan P., Murray, Nicole R. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558152/ https://www.ncbi.nlm.nih.gov/pubmed/25915428 |
Ejemplares similares
-
Protein Kinase C Zeta Regulates Human Pancreatic Cancer Cell Transformed Growth and Invasion through a STAT3-Dependent Mechanism
por: Butler, Amanda M., et al.
Publicado: (2013) -
Prkci Regulates Autophagy and Pancreatic Tumorigenesis in Mice
por: Inman, Kristin S., et al.
Publicado: (2022) -
Protein Kinase C Iota Regulates Pancreatic Acinar-to-Ductal Metaplasia
por: Scotti, Michele L., et al.
Publicado: (2012) -
Protein kinase D1 drives pancreatic acinar cell reprogramming and progression to intraepithelial neoplasia
por: Liou, Geou-Yarh, et al.
Publicado: (2015) -
Protein kinase Cι is required for Ras transformation and colon carcinogenesis in vivo
por: Murray, Nicole R., et al.
Publicado: (2004)