Transcriptional repression of IFNβ1 by ATF2 confers melanoma resistance to therapy

The resistance of melanoma to current treatment modalities represents a major obstacle for durable therapeutic response, and thus, the elucidation of mechanisms of resistance is urgently needed. The crucial functions of Activating Transcription Factor-2 (ATF2) in the development and therapeutic resi...

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Detalles Bibliográficos
Autores principales: Lau, Eric, Sedy, John, Sander, Cindy, Shaw, Misa Austin, Feng, Yongmei, Scortegagna, Marzia, Claps, Giuseppina, Robinson, Steven, Cheng, Phil, Srivas, Rohith, Soonthornvacharin, Stephen, Ideker, Trey, Bosenberg, Marcus, Gonzalez, Réné, Robinson, William, Chanda, Sumit, Ware, Carl, Dummer, Reinhard, Hoon, Dave, Kirkwood, John M., Ronai, Ze'ev A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558399/
https://www.ncbi.nlm.nih.gov/pubmed/25728676
http://dx.doi.org/10.1038/onc.2015.22

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