KAT5-mediated SOX4 acetylation orchestrates chromatin remodeling during myoblast differentiation

Transcription factor SOX4 has been implicated in skeletal myoblast differentiation through the regulation of Cald1 gene expression; however, the detailed molecular mechanism underlying this process is largely unknown. Here, we demonstrate that SOX4 acetylation at lysine 95 by KAT5 (also known as Tip...

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Detalles Bibliográficos
Autores principales: Jang, S-M, Kim, J-W, Kim, C-H, An, J-H, Johnson, A, Song, P I, Rhee, S, Choi, K-H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558493/
https://www.ncbi.nlm.nih.gov/pubmed/26291311
http://dx.doi.org/10.1038/cddis.2015.190

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