Chop deficiency prevents UUO-induced renal fibrosis by attenuating fibrotic signals originated from Hmgb1/TLR4/NFκB/IL-1β signaling

Renal fibrosis, particularly tubulointerstitial fibrosis is considered to be the final manifestation of almost all chronic kidney diseases (CKDs). Herein we demonstrated evidence that CHOP-related ER stress is associated with the development of renal fibrosis in both CKD patients and unilateral uret...

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Detalles Bibliográficos
Autores principales: Zhang, M, Guo, Y, Fu, H, Hu, S, Pan, J, Wang, Y, Cheng, J, Song, J, Yu, Q, Zhang, S, Xu, J-F, Pei, G, Xiang, X, Yang, P, Wang, C-Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558499/
https://www.ncbi.nlm.nih.gov/pubmed/26247732
http://dx.doi.org/10.1038/cddis.2015.206

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