Hexokinase 2 controls cellular stress response through localization of an RNA-binding protein

Subcellular localization of RNA-binding proteins is a key determinant of their ability to control RNA metabolism and cellular stress response. Using an RNAi-based kinome-wide screen, we identified hexokinase 2 (HK2) as a regulator of the cytoplasmic accumulation of hnRNP A1 in response to hypertonic...

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Detalles Bibliográficos
Autores principales: Courteau, L, Crasto, J, Hassanzadeh, G, Baird, S D, Hodgins, J, Liwak-Muir, U, Fung, G, Luo, H, Stojdl, D F, Screaton, R A, Holcik, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558502/
https://www.ncbi.nlm.nih.gov/pubmed/26247723
http://dx.doi.org/10.1038/cddis.2015.209

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