The novel protective role of P27 in MLN4924-treated gastric cancer cells

The tumor-suppressor gene cyclin-dependent kinase inhibitor 1B (P27) is downregulated in gastric cancer cells mainly through proteolytic degradation mediated by the SKP-Cullin1-F-Box (SCF) complex. But the correlation between its downregulation and gastric cancer prognosis still remains indefinite....

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Detalles Bibliográficos
Autores principales: Zhang, Q, Hou, D, Luo, Z, Chen, P, Lv, B, Wu, L, Ma, Y, Chu, Y, Liu, H, Liu, F, Yu, S, Zhang, J, Yang, D, Liu, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558507/
https://www.ncbi.nlm.nih.gov/pubmed/26313918
http://dx.doi.org/10.1038/cddis.2015.215

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558507/
https://www.ncbi.nlm.nih.gov/pubmed/26313918
http://dx.doi.org/10.1038/cddis.2015.215

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