α-Solanine induces ROS-mediated autophagy through activation of endoplasmic reticulum stress and inhibition of Akt/mTOR pathway

α-Solanine is a glycoalkaloid found in species of the nightshade family including potato. It was primarily reported to have toxic effects in humans. However, there is a growing body of literature demonstrating in vitro and in vivo anticancer activity of α-solanine. Most of these studies have shown a...

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Detalles Bibliográficos
Autores principales: Hasanain, M, Bhattacharjee, A, Pandey, P, Ashraf, R, Singh, N, Sharma, S, Vishwakarma, A L, Datta, D, Mitra, K, Sarkar, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558510/
https://www.ncbi.nlm.nih.gov/pubmed/26313911
http://dx.doi.org/10.1038/cddis.2015.219

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558510/
https://www.ncbi.nlm.nih.gov/pubmed/26313911
http://dx.doi.org/10.1038/cddis.2015.219

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