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‘Mutiny on the Bounty’: the genetic history of Norfolk Island reveals extreme gender-biased admixture

BACKGROUND: The Pacific Oceania region was one of the last regions of the world to be settled via human migration. Here we outline a settlement of this region that has given rise to a uniquely admixed population. The current Norfolk Island population has arisen from a small number of founders with m...

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Autores principales: Benton, Miles C., Stuart, Shani, Bellis, Claire, Macartney-Coxson, Donia, Eccles, David, Curran, Joanne E., Chambers, Geoff, Blangero, John, Lea, Rod A., Grffiths, Lyn R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558825/
https://www.ncbi.nlm.nih.gov/pubmed/26339467
http://dx.doi.org/10.1186/s13323-015-0028-9
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author Benton, Miles C.
Stuart, Shani
Bellis, Claire
Macartney-Coxson, Donia
Eccles, David
Curran, Joanne E.
Chambers, Geoff
Blangero, John
Lea, Rod A.
Grffiths, Lyn R.
author_facet Benton, Miles C.
Stuart, Shani
Bellis, Claire
Macartney-Coxson, Donia
Eccles, David
Curran, Joanne E.
Chambers, Geoff
Blangero, John
Lea, Rod A.
Grffiths, Lyn R.
author_sort Benton, Miles C.
collection PubMed
description BACKGROUND: The Pacific Oceania region was one of the last regions of the world to be settled via human migration. Here we outline a settlement of this region that has given rise to a uniquely admixed population. The current Norfolk Island population has arisen from a small number of founders with mixed Caucasian and Polynesian ancestry, descendants of a famous historical event. The ‘Mutiny on the Bounty’ has been told in history books, songs and the big screen, but recently this story can be portrayed through comprehensive molecular genetics. Written history details betrayal and murder leading to the founding of Pitcairn Island by European mutineers and the Polynesian women who left Tahiti with them. Investigation of detailed genealogical records supports historical accounts. FINDINGS: Using genetics, we show distinct maternal Polynesian mitochondrial lineages in the present day population, as well as a European centric Y-chromosome phylogeny. These results comprehensively characterise the unique gender-biased admixture of this genetic isolate and further support the historical records relating to Norfolk Island. CONCLUSIONS: Our results significantly refine previous population genetic studies investigating Polynesian versus Caucasian diversity in the Norfolk Island population and add information that is beneficial to future disease and gene mapping studies. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13323-015-0028-9) contains supplementary material, which is available to authorized users.
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spelling pubmed-45588252015-09-04 ‘Mutiny on the Bounty’: the genetic history of Norfolk Island reveals extreme gender-biased admixture Benton, Miles C. Stuart, Shani Bellis, Claire Macartney-Coxson, Donia Eccles, David Curran, Joanne E. Chambers, Geoff Blangero, John Lea, Rod A. Grffiths, Lyn R. Investig Genet Short Report BACKGROUND: The Pacific Oceania region was one of the last regions of the world to be settled via human migration. Here we outline a settlement of this region that has given rise to a uniquely admixed population. The current Norfolk Island population has arisen from a small number of founders with mixed Caucasian and Polynesian ancestry, descendants of a famous historical event. The ‘Mutiny on the Bounty’ has been told in history books, songs and the big screen, but recently this story can be portrayed through comprehensive molecular genetics. Written history details betrayal and murder leading to the founding of Pitcairn Island by European mutineers and the Polynesian women who left Tahiti with them. Investigation of detailed genealogical records supports historical accounts. FINDINGS: Using genetics, we show distinct maternal Polynesian mitochondrial lineages in the present day population, as well as a European centric Y-chromosome phylogeny. These results comprehensively characterise the unique gender-biased admixture of this genetic isolate and further support the historical records relating to Norfolk Island. CONCLUSIONS: Our results significantly refine previous population genetic studies investigating Polynesian versus Caucasian diversity in the Norfolk Island population and add information that is beneficial to future disease and gene mapping studies. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s13323-015-0028-9) contains supplementary material, which is available to authorized users. BioMed Central 2015-09-03 /pmc/articles/PMC4558825/ /pubmed/26339467 http://dx.doi.org/10.1186/s13323-015-0028-9 Text en © Benton et al. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Short Report
Benton, Miles C.
Stuart, Shani
Bellis, Claire
Macartney-Coxson, Donia
Eccles, David
Curran, Joanne E.
Chambers, Geoff
Blangero, John
Lea, Rod A.
Grffiths, Lyn R.
‘Mutiny on the Bounty’: the genetic history of Norfolk Island reveals extreme gender-biased admixture
title ‘Mutiny on the Bounty’: the genetic history of Norfolk Island reveals extreme gender-biased admixture
title_full ‘Mutiny on the Bounty’: the genetic history of Norfolk Island reveals extreme gender-biased admixture
title_fullStr ‘Mutiny on the Bounty’: the genetic history of Norfolk Island reveals extreme gender-biased admixture
title_full_unstemmed ‘Mutiny on the Bounty’: the genetic history of Norfolk Island reveals extreme gender-biased admixture
title_short ‘Mutiny on the Bounty’: the genetic history of Norfolk Island reveals extreme gender-biased admixture
title_sort ‘mutiny on the bounty’: the genetic history of norfolk island reveals extreme gender-biased admixture
topic Short Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558825/
https://www.ncbi.nlm.nih.gov/pubmed/26339467
http://dx.doi.org/10.1186/s13323-015-0028-9
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