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Granzyme B-inhibitor serpina3n induces neuroprotection in vitro and in vivo

BACKGROUND: Multiple sclerosis (MS) is an autoimmune inflammatory and neurodegenerative disease of the central nervous system (CNS). It is widely accepted that inflammatory cells play major roles in the pathogenesis of MS, possibly through the use of serine protease granzyme B (GrB) secreted from th...

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Detalles Bibliográficos
Autores principales:	Haile, Yohannes, Carmine-Simmen, Katia, Olechowski, Camille, Kerr, Bradley, Bleackley, R. Chris, Giuliani, Fabrizio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558826/ https://www.ncbi.nlm.nih.gov/pubmed/26337722 http://dx.doi.org/10.1186/s12974-015-0376-7

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