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Phylogenetic Analysis Supports a Link between DUF1220 Domain Number and Primate Brain Expansion
The expansion of DUF1220 domain copy number during human evolution is a dramatic example of rapid and repeated domain duplication. Although patterns of expression, homology, and disease associations suggest a role in cortical development, this hypothesis has not been robustly tested using phylogenet...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558844/ https://www.ncbi.nlm.nih.gov/pubmed/26112965 http://dx.doi.org/10.1093/gbe/evv122 |