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The Evolution of Bony Vertebrate Enhancers at Odds with Their Coding Sequence Landscape
Enhancers lie at the heart of transcriptional and developmental gene regulation. Therefore, changes in enhancer sequences usually disrupt the target gene expression and result in disease phenotypes. Despite the well-established role of enhancers in development and disease, evolutionary sequence stud...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558863/ https://www.ncbi.nlm.nih.gov/pubmed/26253316 http://dx.doi.org/10.1093/gbe/evv146 |