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Enantioselective Synthesis of Carbo- and Heterocycles through a CuH-Catalyzed Hydroalkylation Approach
[Image: see text] The enantioselective, intramolecular hydroalkylation of halide-tethered styrenes has been achieved through a copper hydride-catalyzed process. This approach allowed for the synthesis of enantioenriched cyclobutanes, cyclopentanes, indanes, and six-membered N- and O-heterocycles. Th...
Autores principales: | Wang, Yi-Ming, Bruno, Nicholas C., Placeres, Ángel L., Zhu, Shaolin, Buchwald, Stephen L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2015
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4558994/ https://www.ncbi.nlm.nih.gov/pubmed/26256576 http://dx.doi.org/10.1021/jacs.5b07061 |
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