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miRNAs and SAMHD1 regulation in vitro and in a model of HIV CNS disease
Pilakka-Kanthikeel et al. recently reported higher levels of the retroviral restriction factor sterile alpha motif and histidine/aspartic acid domain-containing protein 1 (SAMHD1) in astrocytes than in microglia, suggesting that SAMHD1 levels might explain in part the relatively refractory nature of...
Autores principales: | Witwer, Kenneth W., Buchanan, Erin L., Myers, Stephanie L., McAlexander, Melissa A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559003/ https://www.ncbi.nlm.nih.gov/pubmed/26337901 http://dx.doi.org/10.1186/s12974-015-0380-y |
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