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Isoniazid-induced polyneuropathy in a tuberculosis patient – implication for individual risk stratification with genotyping?
BACKGROUND: Development of polyneuropathy (PNP) under treatment for tuberculosis (TB), including isoniazid (INH), is a highly relevant adverse drug effect. The NAT2 acetylation status is a predictor of potential toxic effects of INH. The question as to whether individual risk stratification by genot...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley & Sons, Ltd
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559012/ https://www.ncbi.nlm.nih.gov/pubmed/26355945 http://dx.doi.org/10.1002/brb3.326 |