Genomic alterations in DNA repair and chromatin remodeling genes in estrogen receptor-positive metastatic breast cancer patients with exceptional responses to capecitabine

We analyzed the genomic and phosphoproteomic profiles of breast cancer tissue obtained from six patients with estrogen receptor (ER)-positive, HER2-negative metastatic breast cancer who had highly durable (≥5 years) and, in some cases, ongoing clinical responses with capecitabine. Formalin-fixed, pa...

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Detalles Bibliográficos
Autores principales: Levin, Maren K, Wang, Kai, Yelensky, Roman, Cao, Ying, Ramos, Corinne, Hoke, Nicholas, Pippen, John, Blum, Joanne L, Brooks, Barry, Palmer, Gary, Palma, Norma, Balasubramanian, Sohail, Ross, Jeffrey S, O’Shaughnessy, Joyce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Ltd 2015
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559040/
https://www.ncbi.nlm.nih.gov/pubmed/25871911
http://dx.doi.org/10.1002/cam4.464

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