Serially coupling hydrophobic interaction and reversed-phase chromatography with simultaneous gradients provides greater coverage of the metabolome

The serial coupling of a reversed-phase liquid chromatography (RPLC) column to a hydrophilic interaction liquid chromatography (HILIC) column has been developed in recent years for the detection of polar and nonpolar metabolites. TCA intermediates, bile acid standards and numerous polar and non-pola...

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Detalles Bibliográficos
Autores principales: Haggarty, Jennifer, Oppermann, Madalina, Dalby, Matthew J., Burchmore, Richard J., Cook, Ken, Weidt, Stefan, Burgess, Karl E. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559102/
https://www.ncbi.nlm.nih.gov/pubmed/26366140
http://dx.doi.org/10.1007/s11306-014-0770-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559102/
https://www.ncbi.nlm.nih.gov/pubmed/26366140
http://dx.doi.org/10.1007/s11306-014-0770-7

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