Oxidative stress–induced mitochondrial dysfunction drives inflammation and airway smooth muscle remodeling in patients with chronic obstructive pulmonary disease

BACKGROUND: Inflammation and oxidative stress play critical roles in patients with chronic obstructive pulmonary disease (COPD). Mitochondrial oxidative stress might be involved in driving the oxidative stress–induced pathology. OBJECTIVE: We sought to determine the effects of oxidative stress on mi...

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Detalles Bibliográficos
Autores principales: Wiegman, Coen H., Michaeloudes, Charalambos, Haji, Gulammehdi, Narang, Priyanka, Clarke, Colin J., Russell, Kirsty E., Bao, Wuping, Pavlidis, Stelios, Barnes, Peter J., Kanerva, Justin, Bittner, Anton, Rao, Navin, Murphy, Michael P., Kirkham, Paul A., Chung, Kian Fan, Adcock, Ian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mosby 2015
Materias:
Mechanisms of Allergy and Clinical Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559140/
https://www.ncbi.nlm.nih.gov/pubmed/25828268
http://dx.doi.org/10.1016/j.jaci.2015.01.046

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