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Patient-derived heavy chain antibody targets cell surface HSP90 on breast tumors
BACKGROUND: Monoclonal antibodies have been used to effectively treat various tumors. We previously established a unique strategy to identify tumor specific antibodies by capturing B-cell response against breast tumor antigens from patient-derived sentinel lymph nodes. Initial application of this ap...
Autores principales: | Devarakonda, Charan V., Kita, Daniel, Phoenix, Kathryn N., Claffey, Kevin P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559304/ https://www.ncbi.nlm.nih.gov/pubmed/26334999 http://dx.doi.org/10.1186/s12885-015-1608-z |
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