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Multi-objective optimization for RNA design with multiple target secondary structures
BACKGROUND: RNAs are attractive molecules as the biological parts for synthetic biology. In particular, the ability of conformational changes, which can be encoded in designer RNAs, enables us to create multistable molecular switches that function in biological circuits. Although various algorithms...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559319/ https://www.ncbi.nlm.nih.gov/pubmed/26335276 http://dx.doi.org/10.1186/s12859-015-0706-x |