The alternatively spliced fibronectin CS1 isoform regulates IL-17A levels and mechanical allodynia after peripheral nerve injury

BACKGROUND: Mechanical pain hypersensitivity associated with physical trauma to peripheral nerve depends on T-helper (Th) cells expressing the algesic cytokine, interleukin (IL)-17A. Fibronectin (FN) isoform alternatively spliced within the IIICS region encoding the 25-residue-long connecting segmen...

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Detalles Bibliográficos
Autores principales: Liu, Huaqing, Dolkas, Jennifer, Hoang, Khan, Angert, Mila, Chernov, Andrei V., Remacle, Albert G., Shiryaev, Sergey A., Strongin, Alex Y., Nishihara, Tasuku, Shubayev, Veronica I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559385/
https://www.ncbi.nlm.nih.gov/pubmed/26337825
http://dx.doi.org/10.1186/s12974-015-0377-6

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