Immunostimulatory Defective Viral Genomes from Respiratory Syncytial Virus Promote a Strong Innate Antiviral Response during Infection in Mice and Humans

Human respiratory syncytial virus (RSV) is a major cause of severe respiratory illness in children and susceptible adults. RSV blocks the development of the innate antiviral immune response and can grow to high titers in the respiratory tract. Here we demonstrate that immunostimulatory defective vir...

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Detalles Bibliográficos
Autores principales: Sun, Yan, Jain, Deepika, Koziol-White, Cynthia J., Genoyer, Emmanuelle, Gilbert, Micah, Tapia, Karla, Panettieri, Reynold A., Hodinka, Richard L., López, Carolina B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559413/
https://www.ncbi.nlm.nih.gov/pubmed/26336095
http://dx.doi.org/10.1371/journal.ppat.1005122

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