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Schistosoma mansoni Infection in Ugandan Men Is Associated with Increased Abundance and Function of HIV Target Cells in Blood, but Not the Foreskin: A Cross-sectional Study

BACKGROUND: Schistosoma mansoni infection has been associated with an increased HIV prevalence in humans and SHIV incidence in primate models. We hypothesized that immune activation from this gastrointestinal mucosa infection would increase highly HIV-susceptible CD4 T cell subsets in the blood and...

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Detalles Bibliográficos
Autores principales: Prodger, Jessica L., Ssemaganda, Aloysious, Ssetaala, Ali, Kitandwe, Paul K., Muyanja, Enoch, Mpendo, Juliet, Nanvubya, Annet, Wambuzi, Mathias, Nielsen, Leslie, Kiwanuka, Noah, Kaul, Rupert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559468/
https://www.ncbi.nlm.nih.gov/pubmed/26335139
http://dx.doi.org/10.1371/journal.pntd.0004067