Draft Genome Sequence of a Metronidazole-Susceptible Atopobium vaginae Isolate

We report the draft genome sequence of a vaginal isolate of Atopobium vaginae vaginae (strain 44061), an organism linked to bacterial vaginosis (BV), the most common gynecological infection in the United States. This species is often highly resistant to metronidazole, which is a front-line therapy f...

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Detalles Bibliográficos
Autores principales: Schuyler, Jessica A., Mordechai, Eli, Adelson, Martin E., Gygax, Scott E., Hilbert, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559735/
https://www.ncbi.nlm.nih.gov/pubmed/26337886
http://dx.doi.org/10.1128/genomeA.00991-15
Descripción
Sumario:We report the draft genome sequence of a vaginal isolate of Atopobium vaginae vaginae (strain 44061), an organism linked to bacterial vaginosis (BV), the most common gynecological infection in the United States. This species is often highly resistant to metronidazole, which is a front-line therapy for BV. Strain 44061 is a metronidazole-susceptible isolate (MIC, 16 µg/ml), and its genome sequence will be useful for comparative studies to elucidate the molecular basis of metronidazole resistance in this species.

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