Draft Genome Sequence of a Metronidazole-Susceptible Atopobium vaginae Isolate

We report the draft genome sequence of a vaginal isolate of Atopobium vaginae vaginae (strain 44061), an organism linked to bacterial vaginosis (BV), the most common gynecological infection in the United States. This species is often highly resistant to metronidazole, which is a front-line therapy f...

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Autores principales: Schuyler, Jessica A., Mordechai, Eli, Adelson, Martin E., Gygax, Scott E., Hilbert, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559735/
https://www.ncbi.nlm.nih.gov/pubmed/26337886
http://dx.doi.org/10.1128/genomeA.00991-15
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author Schuyler, Jessica A.
Mordechai, Eli
Adelson, Martin E.
Gygax, Scott E.
Hilbert, David W.
author_facet Schuyler, Jessica A.
Mordechai, Eli
Adelson, Martin E.
Gygax, Scott E.
Hilbert, David W.
author_sort Schuyler, Jessica A.
collection PubMed
description We report the draft genome sequence of a vaginal isolate of Atopobium vaginae vaginae (strain 44061), an organism linked to bacterial vaginosis (BV), the most common gynecological infection in the United States. This species is often highly resistant to metronidazole, which is a front-line therapy for BV. Strain 44061 is a metronidazole-susceptible isolate (MIC, 16 µg/ml), and its genome sequence will be useful for comparative studies to elucidate the molecular basis of metronidazole resistance in this species.
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spelling pubmed-45597352015-09-04 Draft Genome Sequence of a Metronidazole-Susceptible Atopobium vaginae Isolate Schuyler, Jessica A. Mordechai, Eli Adelson, Martin E. Gygax, Scott E. Hilbert, David W. Genome Announc Prokaryotes We report the draft genome sequence of a vaginal isolate of Atopobium vaginae vaginae (strain 44061), an organism linked to bacterial vaginosis (BV), the most common gynecological infection in the United States. This species is often highly resistant to metronidazole, which is a front-line therapy for BV. Strain 44061 is a metronidazole-susceptible isolate (MIC, 16 µg/ml), and its genome sequence will be useful for comparative studies to elucidate the molecular basis of metronidazole resistance in this species. American Society for Microbiology 2015-09-03 /pmc/articles/PMC4559735/ /pubmed/26337886 http://dx.doi.org/10.1128/genomeA.00991-15 Text en Copyright © 2015 Schuyler et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) .
spellingShingle Prokaryotes
Schuyler, Jessica A.
Mordechai, Eli
Adelson, Martin E.
Gygax, Scott E.
Hilbert, David W.
Draft Genome Sequence of a Metronidazole-Susceptible Atopobium vaginae Isolate
title Draft Genome Sequence of a Metronidazole-Susceptible Atopobium vaginae Isolate
title_full Draft Genome Sequence of a Metronidazole-Susceptible Atopobium vaginae Isolate
title_fullStr Draft Genome Sequence of a Metronidazole-Susceptible Atopobium vaginae Isolate
title_full_unstemmed Draft Genome Sequence of a Metronidazole-Susceptible Atopobium vaginae Isolate
title_short Draft Genome Sequence of a Metronidazole-Susceptible Atopobium vaginae Isolate
title_sort draft genome sequence of a metronidazole-susceptible atopobium vaginae isolate
topic Prokaryotes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559735/
https://www.ncbi.nlm.nih.gov/pubmed/26337886
http://dx.doi.org/10.1128/genomeA.00991-15
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