Draft Genome Sequence of a Metronidazole-Resistant Gardnerella vaginalis Isolate

We report the draft genome sequence of a Gardnerella vaginalis strain (3549624) isolated from a vaginal specimen. G. vaginalis is associated with bacterial vaginosis, the most common cause of vaginal discharge, which is often treated with metronidazole. This isolate is highly resistant to metronidaz...

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Detalles Bibliográficos
Autores principales: Schuyler, Jessica A., Chadwick, Sean G., Mordechai, Eli, Adelson, Martin E., Gygax, Scott E., Hilbert, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559736/
https://www.ncbi.nlm.nih.gov/pubmed/26337887
http://dx.doi.org/10.1128/genomeA.00992-15
Descripción
Sumario:We report the draft genome sequence of a Gardnerella vaginalis strain (3549624) isolated from a vaginal specimen. G. vaginalis is associated with bacterial vaginosis, the most common cause of vaginal discharge, which is often treated with metronidazole. This isolate is highly resistant to metronidazole (MIC, 500 µg/ml) and may be useful for comparative genomic studies to determine the molecular basis of metronidazole resistance in this species.

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