Draft Genome Sequence of a Metronidazole-Resistant Gardnerella vaginalis Isolate

We report the draft genome sequence of a Gardnerella vaginalis strain (3549624) isolated from a vaginal specimen. G. vaginalis is associated with bacterial vaginosis, the most common cause of vaginal discharge, which is often treated with metronidazole. This isolate is highly resistant to metronidaz...

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Detalles Bibliográficos
Autores principales: Schuyler, Jessica A., Chadwick, Sean G., Mordechai, Eli, Adelson, Martin E., Gygax, Scott E., Hilbert, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Prokaryotes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559736/
https://www.ncbi.nlm.nih.gov/pubmed/26337887
http://dx.doi.org/10.1128/genomeA.00992-15
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author Schuyler, Jessica A.
Chadwick, Sean G.
Mordechai, Eli
Adelson, Martin E.
Gygax, Scott E.
Hilbert, David W.
author_facet Schuyler, Jessica A.
Chadwick, Sean G.
Mordechai, Eli
Adelson, Martin E.
Gygax, Scott E.
Hilbert, David W.
author_sort Schuyler, Jessica A.
collection PubMed
description We report the draft genome sequence of a Gardnerella vaginalis strain (3549624) isolated from a vaginal specimen. G. vaginalis is associated with bacterial vaginosis, the most common cause of vaginal discharge, which is often treated with metronidazole. This isolate is highly resistant to metronidazole (MIC, 500 µg/ml) and may be useful for comparative genomic studies to determine the molecular basis of metronidazole resistance in this species.
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spelling pubmed-45597362015-09-04 Draft Genome Sequence of a Metronidazole-Resistant Gardnerella vaginalis Isolate Schuyler, Jessica A. Chadwick, Sean G. Mordechai, Eli Adelson, Martin E. Gygax, Scott E. Hilbert, David W. Genome Announc Prokaryotes We report the draft genome sequence of a Gardnerella vaginalis strain (3549624) isolated from a vaginal specimen. G. vaginalis is associated with bacterial vaginosis, the most common cause of vaginal discharge, which is often treated with metronidazole. This isolate is highly resistant to metronidazole (MIC, 500 µg/ml) and may be useful for comparative genomic studies to determine the molecular basis of metronidazole resistance in this species. American Society for Microbiology 2015-09-03 /pmc/articles/PMC4559736/ /pubmed/26337887 http://dx.doi.org/10.1128/genomeA.00992-15 Text en Copyright © 2015 Schuyler et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) .
spellingShingle Prokaryotes
Schuyler, Jessica A.
Chadwick, Sean G.
Mordechai, Eli
Adelson, Martin E.
Gygax, Scott E.
Hilbert, David W.
Draft Genome Sequence of a Metronidazole-Resistant Gardnerella vaginalis Isolate
title Draft Genome Sequence of a Metronidazole-Resistant Gardnerella vaginalis Isolate
title_full Draft Genome Sequence of a Metronidazole-Resistant Gardnerella vaginalis Isolate
title_fullStr Draft Genome Sequence of a Metronidazole-Resistant Gardnerella vaginalis Isolate
title_full_unstemmed Draft Genome Sequence of a Metronidazole-Resistant Gardnerella vaginalis Isolate
title_short Draft Genome Sequence of a Metronidazole-Resistant Gardnerella vaginalis Isolate
title_sort draft genome sequence of a metronidazole-resistant gardnerella vaginalis isolate
topic Prokaryotes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559736/
https://www.ncbi.nlm.nih.gov/pubmed/26337887
http://dx.doi.org/10.1128/genomeA.00992-15
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