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A novel recombinant slow-release TNF α-derived peptide effectively inhibits tumor growth and angiogensis

RMP16, a recombinant TNF α-derived polypeptide comprising a specific human serum albumin (HSA)-binding 7-mer peptide identified by phage display screening (WQRPSSW), a cleavage peptide for Factor Xa (IEGR), and a 20-amino acid bioactive peptide P16 (TNF α segment including amino acid residues 75–94)...

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Detalles Bibliográficos
Autores principales: Ma, Yi, Zhao, Shaojun, Shen, Shutao, Fang, Shixiong, Ye, Zulu, Shi, Zhi, Hong, An
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559766/
https://www.ncbi.nlm.nih.gov/pubmed/26337231
http://dx.doi.org/10.1038/srep13595