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A novel recombinant slow-release TNF α-derived peptide effectively inhibits tumor growth and angiogensis
RMP16, a recombinant TNF α-derived polypeptide comprising a specific human serum albumin (HSA)-binding 7-mer peptide identified by phage display screening (WQRPSSW), a cleavage peptide for Factor Xa (IEGR), and a 20-amino acid bioactive peptide P16 (TNF α segment including amino acid residues 75–94)...
Autores principales: | Ma, Yi, Zhao, Shaojun, Shen, Shutao, Fang, Shixiong, Ye, Zulu, Shi, Zhi, Hong, An |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559766/ https://www.ncbi.nlm.nih.gov/pubmed/26337231 http://dx.doi.org/10.1038/srep13595 |
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