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Carbon ions induce autophagy effectively through stimulating the unfolded protein response and subsequent inhibiting Akt phosphorylation in tumor cells

Heavy ion beams have advantages over conventional radiation in radiotherapy due to their superb biological effectiveness and dose conformity. However, little information is currently available concerning the cellular and molecular basis for heavy ion radiation-induced autophagy. In this study, human...

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Detalles Bibliográficos
Autores principales: Jin, Xiaodong, Li, Feifei, Zheng, Xiaogang, Liu, Yan, Hirayama, Ryoichi, Liu, Xiongxiong, Li, Ping, Zhao, Ting, Dai, Zhongying, Li, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559768/
https://www.ncbi.nlm.nih.gov/pubmed/26338671
http://dx.doi.org/10.1038/srep13815

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