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Direct reprogramming of mouse fibroblasts into cardiomyocytes with chemical cocktails

The direct conversion, or transdifferentiation, of non-cardiac cells into cardiomyocytes by forced expression of transcription factors and microRNAs provides promising approaches for cardiac regeneration. However, genetic manipulations raise safety concerns and are thus not desirable in most clinica...

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Detalles Bibliográficos
Autores principales: Fu, Yanbin, Huang, Chenwen, Xu, Xinxiu, Gu, Haifeng, Ye, Youqiong, Jiang, Cizhong, Qiu, Zilong, Xie, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559819/
https://www.ncbi.nlm.nih.gov/pubmed/26292833
http://dx.doi.org/10.1038/cr.2015.99