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Direct reprogramming of mouse fibroblasts into cardiomyocytes with chemical cocktails
The direct conversion, or transdifferentiation, of non-cardiac cells into cardiomyocytes by forced expression of transcription factors and microRNAs provides promising approaches for cardiac regeneration. However, genetic manipulations raise safety concerns and are thus not desirable in most clinica...
Autores principales: | Fu, Yanbin, Huang, Chenwen, Xu, Xinxiu, Gu, Haifeng, Ye, Youqiong, Jiang, Cizhong, Qiu, Zilong, Xie, Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559819/ https://www.ncbi.nlm.nih.gov/pubmed/26292833 http://dx.doi.org/10.1038/cr.2015.99 |
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