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A septo-temporal molecular gradient of sfrp3 in the dentate gyrus differentially regulates quiescent adult hippocampal neural stem cell activation
BACKGROUND: A converging body of evidence indicates that levels of adult hippocampal neurogenesis vary along the septo-temporal axis of the dentate gyrus, but the molecular mechanisms underlying this regional heterogeneity are not known. We previously identified a niche mechanism regulating prolifer...
Autores principales: | Sun, Jiaqi, Bonaguidi, Michael A., Jun, Heechul, Guo, Junjie U., Sun, Gerald J., Will, Brett, Yang, Zhengang, Jang, Mi-Hyeon, Song, Hongjun, Ming, Guo-li, Christian, Kimberly M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559945/ https://www.ncbi.nlm.nih.gov/pubmed/26337530 http://dx.doi.org/10.1186/s13041-015-0143-9 |
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