Wss1 metalloprotease partners with Cdc48/Doa1 in processing genotoxic SUMO conjugates

Sumoylation during genotoxic stress regulates the composition of DNA repair complexes. The yeast metalloprotease Wss1 clears chromatin-bound sumoylated proteins. Wss1 and its mammalian analog, DVC1/Spartan, belong to minigluzincins family of proteases. Wss1 proteolytic activity is regulated by a cys...

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Detalles Bibliográficos
Autores principales: Balakirev, Maxim Y, Mullally, James E, Favier, Adrien, Assard, Nicole, Sulpice, Eric, Lindsey, David F, Rulina, Anastasia V, Gidrol, Xavier, Wilkinson, Keith D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Biochemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559962/
https://www.ncbi.nlm.nih.gov/pubmed/26349035
http://dx.doi.org/10.7554/eLife.06763

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559962/
https://www.ncbi.nlm.nih.gov/pubmed/26349035
http://dx.doi.org/10.7554/eLife.06763

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