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P2X7 receptor-mediated PARP1 activity regulates astroglial death in the rat hippocampus following status epilepticus
Poly(ADP-ribose) polymerase-1 (PARP1) plays a regulatory role in apoptosis, necrosis, and other cellular processes after injury. Recently, we revealed that PARP1 regulates the differential neuronal/astroglial responses to pilocarpine-induced status epilepticus (SE) in the distinct brain regions. In...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560025/ https://www.ncbi.nlm.nih.gov/pubmed/26388738 http://dx.doi.org/10.3389/fncel.2015.00352 |