Mesoangioblast delivery of miniagrin ameliorates murine model of merosin-deficient congenital muscular dystrophy type 1A

BACKGROUND: Merosin-deficient congenital muscular dystrophy type-1A (MDC1A) is characterized by progressive muscular dystrophy and dysmyelinating neuropathy caused by mutations of the α2 chain of laminin-211, the predominant laminin isoform of muscles and nerves. MDC1A has no available treatment so...

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Detalles Bibliográficos
Autores principales: Domi, Teuta, Porrello, Emanuela, Velardo, Daniele, Capotondo, Alessia, Biffi, Alessandra, Tonlorenzi, Rossana, Amadio, Stefano, Ambrosi, Alessandro, Miyagoe-Suzuki, Yuko, Takeda, Shin’ichi, Ruegg, Markus A., Previtali, Stefano Carlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560053/
https://www.ncbi.nlm.nih.gov/pubmed/26347253
http://dx.doi.org/10.1186/s13395-015-0055-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560053/
https://www.ncbi.nlm.nih.gov/pubmed/26347253
http://dx.doi.org/10.1186/s13395-015-0055-5

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