Cargando…

Variation at interleukin-6 receptor gene is associated to joint damage in rheumatoid arthritis

INTRODUCTION: Interleukin-6 (IL-6) cytokine signaling is key in Rheumatoid Arthritis (RA) pathophysiology. Blocking IL-6 receptor (IL6R) has proven to be a highly effective treatment to prevent joint damage. This study was performed to investigate the association between the genetic variation at IL6...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lopez-Lasanta, Maria, Julià, Antonio, Maymó, Joan, Fernández-Gutierrez, Benjamín, Ureña-Garnica, Inmaculada, Blanco, Francisco J., Cañete, Juan D., Alperi-López, Mercedes, Olivè, Alex, Corominas, Héctor, Tornero, Jesus, Erra, Alba, Almirall, Miriam, Palau, Nuria, Ortiz, Ana, Avila, Gabriela, Rodriguez-Rodriguez, Luis, Alonso, Arnald, Tortosa, Raül, Gonzalez-Alvaro, Isidoro, Marsal, Sara
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560075/ https://www.ncbi.nlm.nih.gov/pubmed/26336855 http://dx.doi.org/10.1186/s13075-015-0737-8

Ejemplares similares

A Combined Transcriptomic and Genomic Analysis Identifies a Gene Signature Associated With the Response to Anti-TNF Therapy in Rheumatoid Arthritis
por: Aterido, Adrià, et al.
Publicado: (2019)

Variation at FCGR2A and Functionally Related Genes Is Associated with the Response to Anti-TNF Therapy in Rheumatoid Arthritis
por: Avila-Pedretti, Gabriela, et al.
Publicado: (2015)

Interactions between rheumatoid arthritis antibodies are associated with the response to anti-tumor necrosis factor therapy
por: Julià, Antonio, et al.
Publicado: (2021)

CNstream: A method for the identification and genotyping of copy number polymorphisms using Illumina microarrays
por: Alonso, Arnald, et al.
Publicado: (2010)

Genome-wide transcriptional analysis of T cell activation reveals differential gene expression associated with psoriasis
por: Palau, Nuria, et al.
Publicado: (2013)

Longitudinal analysis of blood DNA methylation identifies mechanisms of response to tumor necrosis factor inhibitor therapy in rheumatoid arthritis
por: Julià, Antonio, et al.
Publicado: (2022)

Genetic variation associated with cardiovascular risk in autoimmune diseases
por: Perrotti, Pedro P., et al.
Publicado: (2017)

GStream: Improving SNP and CNV Coverage on Genome-Wide Association Studies
por: Alonso, Arnald, et al.
Publicado: (2013)

IMID-Biobank: Biobank of immune-mediated inflammatory diseases (IMIDs)
por: Marsal, S, et al.
Publicado: (2010)

Urine metabolome profiling of immune-mediated inflammatory diseases
por: Alonso, Arnald, et al.
Publicado: (2016)

Incidence of COVID-19 in a cohort of adult and paediatric patients with rheumatic diseases treated with targeted biologic and synthetic disease-modifying anti-rheumatic drugs
por: Michelena, Xabier, et al.
Publicado: (2020)

Analytical Methods in Untargeted Metabolomics: State of the Art in 2015
por: Alonso, Arnald, et al.
Publicado: (2015)

Genome-wide pathway analysis identifies VEGF pathway association with oral ulceration in systemic lupus erythematosus
por: Aterido, Adrià, et al.
Publicado: (2017)

Non-Esterified Fatty Acids Profiling in Rheumatoid Arthritis: Associations with Clinical Features and Th1 Response
por: Rodríguez-Carrio, Javier, et al.
Publicado: (2016)

Heterogeneity of the Type I Interferon Signature in Rheumatoid Arthritis: A Potential Limitation for Its Use As a Clinical Biomarker
por: Rodríguez-Carrio, Javier, et al.
Publicado: (2018)

Profiling of B-Cell Factors and Their Decoy Receptors in Rheumatoid Arthritis: Association With Clinical Features and Treatment Outcomes
por: Rodríguez-Carrio, Javier, et al.
Publicado: (2018)

IRF4 and IRGs Delineate Clinically Relevant Gene Expression Signatures in Systemic Lupus Erythematosus and Rheumatoid Arthritis
por: Rodríguez-Carrio, Javier, et al.
Publicado: (2019)

Targeting of the CD80/86 proinflammatory axis as a therapeutic strategy to prevent severe COVID-19
por: Julià, Antonio, et al.
Publicado: (2021)

An Eight-Gene Blood Expression Profile Predicts the Response to Infliximab in Rheumatoid Arthritis
por: Julià, Antonio, et al.
Publicado: (2009)

IFNα Serum Levels Are Associated with Endothelial Progenitor Cells Imbalance and Disease Features in Rheumatoid Arthritis Patients
por: Rodríguez-Carrio, Javier, et al.
Publicado: (2014)

GlycA Levels during the Earliest Stages of Rheumatoid Arthritis: Potential Use as a Biomarker of Subclinical Cardiovascular Disease
por: Rodríguez-Carrio, Javier, et al.
Publicado: (2020)

Cardiovascular disease in immune-mediated inflammatory diseases: A cross-sectional analysis of 6 cohorts
por: Fernández-Gutiérrez, Benjamín, et al.
Publicado: (2017)

Vitamin D Receptor Polymorphism and DHCR7 Contribute to the Abnormal Interplay Between Vitamin D and Lipid Profile in Rheumatoid Arthritis
por: Rodríguez-Carrio, Javier, et al.
Publicado: (2019)

Do NSAIDs Take Us Away From Treatment Goals in Axial Spondyloarthritis: A Story About Dysbiosis or Just a Matter of Bias?
por: Queiro-Silva, Rubén, et al.
Publicado: (2021)

Genome-wide association study meta-analysis identifies five new loci for systemic lupus erythematosus
por: Julià, Antonio, et al.
Publicado: (2018)

Lower peripheral helper T cell levels in the synovium are associated with a better response to anti-TNF therapy in rheumatoid arthritis
por: Julià, Antonio, et al.
Publicado: (2020)

Synovial lymphoid neogenesis is associated with IL-23 expression and disease activity in rheumatoid arthritis
por: Cañete, Juan D, et al.
Publicado: (2011)

Prenatal Diagnosis of Neu–Laxova Syndrome
por: Serrano Olave, Adriana, et al.
Publicado: (2022)

HLA-C locus alleles may modulate the clinical expression of psoriatic arthritis
por: Queiro, Ruben, et al.
Publicado: (2006)

Non-Physical Disease Facets in Spondyloarthritis: An ASAS Health Index-Based Analysis between Psoriatic Arthritis and Axial Spondyloarthritis
por: Queiro, Rubén, et al.
Publicado: (2022)

Potential Benefits of the Self-Administration of Subcutaneous Methotrexate with Autoinjector Devices for Patients: A Review
por: Tornero Molina, Jesús, et al.
Publicado: (2021)

Cabut/dTIEG associates with the transcription factor Yorkie for growth control
por: Ruiz-Romero, Marina, et al.
Publicado: (2015)

Deciphering the Adjustment between Environment and Life History in Annuals: Lessons from a Geographically-Explicit Approach in Arabidopsis thaliana
por: Manzano-Piedras, Esperanza, et al.
Publicado: (2014)

Tackling intraspecific genetic structure in distribution models better reflects species geographical range
por: Marcer, Arnald, et al.
Publicado: (2016)

The relevance of transversal competences in vocational education and training: a bibliometric analysis
por: Calero López, Inmaculada, et al.
Publicado: (2020)

Aplicación de un método natural de planificación familiar en una población rural, Campo Chico, Ver.
por: Rodríguez Garnica, Esthela
Publicado: (1997)

Arthroscopic Treatment of Chronic Acromioclavicular Dislocation With Semitendinosus Autograft and Coracoclavicular Suspension Fixation
por: Cañete San Pastor, Pablo, et al.
Publicado: (2022)

Mediation Effect of Age Category on the Relationship between Body Composition and the Physical Fitness Profile in Youth Handball Players
por: Molina-López, Jorge, et al.
Publicado: (2020)

Characterising the axial phenotype of psoriatic arthritis: a study comparing axial psoriatic arthritis and ankylosing spondylitis with psoriasis from the REGISPONSER registry
por: Michelena, Xabier, et al.
Publicado: (2022)

Valve Abnormalities, Risk Factors for Heart Valve Disease and Valve Replacement Surgery in Spondyloarthritis. A Systematic Review of the Literature
por: Park, Hye-Sang, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_fudokt6tmudoceaee6daiue10i