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Hepatic angiomyolipoma with special attention to radiologic imaging
BACKGROUND: Angiomyolipoma is a unique mesenchymal neoplasm composed of blood vessels as well as smooth muscle and adipose cells. The liver is a less common site of origin, and hepatic angiomyolipoma is often an incidental finding on diagnostic imaging or is identified on evaluation of nonspecific s...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560139/ https://www.ncbi.nlm.nih.gov/pubmed/26366342 http://dx.doi.org/10.1186/s40792-015-0038-0 |
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author | Kuramoto, Kunitaka Beppu, Toru Namimoto, Tomohiro Hayashi, Hiromitsu Imai, Katsunori Nitta, Hidetoshi Hashimoto, Daisuke Chikamoto, Akira Ishiko, Takatoshi Iyama, Ken-Ichi Ikeda, Osamu Yamashita, Yasuyuki Baba, Hideo |
author_facet | Kuramoto, Kunitaka Beppu, Toru Namimoto, Tomohiro Hayashi, Hiromitsu Imai, Katsunori Nitta, Hidetoshi Hashimoto, Daisuke Chikamoto, Akira Ishiko, Takatoshi Iyama, Ken-Ichi Ikeda, Osamu Yamashita, Yasuyuki Baba, Hideo |
author_sort | Kuramoto, Kunitaka |
collection | PubMed |
description | BACKGROUND: Angiomyolipoma is a unique mesenchymal neoplasm composed of blood vessels as well as smooth muscle and adipose cells. The liver is a less common site of origin, and hepatic angiomyolipoma is often an incidental finding on diagnostic imaging or is identified on evaluation of nonspecific symptoms. CASE PRESENTATION: We experienced four patients who were diagnosed histologically with hepatic angiomyolipoma. The preoperative diagnoses were angiomyolipoma in two patients, hepatocellular carcinoma in one, and cavernous hemangioma in one. Three patients were treated with hepatectomy (one laparoscopic and two open approaches), and the diagnosis was completed by histological investigation of the resected specimen. The remaining one was diagnosed from tumor needle biopsy. Diffusion-weighted magnetic resonance imaging (MRI) with respiratory triggering using b values of 0 and 800 s/mm(2) was employed. An apparent diffusion coefficient map was generated from b values of 0 and 800 s/mm(2) for calculation of the apparent diffusion coefficient. The apparent diffusion coefficient values were calculated as 3.66, 1.21, 1.80, and 0.91 in patients 1 to 4, respectively. In MRI imaging, fat component was clearly demonstrated with chemical shift imaging in three patients. Early venous return was detected in three patients with computed tomography angiography. CONCLUSION: Fat component and early venous return are important for a correct diagnosis of hepatic angiomyolipoma. Unfortunately, apparent diffusion coefficient values in hepatic angiomyolipoma were overlapping with those in other benign and malignant tumors. |
format | Online Article Text |
id | pubmed-4560139 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-45601392015-09-10 Hepatic angiomyolipoma with special attention to radiologic imaging Kuramoto, Kunitaka Beppu, Toru Namimoto, Tomohiro Hayashi, Hiromitsu Imai, Katsunori Nitta, Hidetoshi Hashimoto, Daisuke Chikamoto, Akira Ishiko, Takatoshi Iyama, Ken-Ichi Ikeda, Osamu Yamashita, Yasuyuki Baba, Hideo Surg Case Rep Case Report BACKGROUND: Angiomyolipoma is a unique mesenchymal neoplasm composed of blood vessels as well as smooth muscle and adipose cells. The liver is a less common site of origin, and hepatic angiomyolipoma is often an incidental finding on diagnostic imaging or is identified on evaluation of nonspecific symptoms. CASE PRESENTATION: We experienced four patients who were diagnosed histologically with hepatic angiomyolipoma. The preoperative diagnoses were angiomyolipoma in two patients, hepatocellular carcinoma in one, and cavernous hemangioma in one. Three patients were treated with hepatectomy (one laparoscopic and two open approaches), and the diagnosis was completed by histological investigation of the resected specimen. The remaining one was diagnosed from tumor needle biopsy. Diffusion-weighted magnetic resonance imaging (MRI) with respiratory triggering using b values of 0 and 800 s/mm(2) was employed. An apparent diffusion coefficient map was generated from b values of 0 and 800 s/mm(2) for calculation of the apparent diffusion coefficient. The apparent diffusion coefficient values were calculated as 3.66, 1.21, 1.80, and 0.91 in patients 1 to 4, respectively. In MRI imaging, fat component was clearly demonstrated with chemical shift imaging in three patients. Early venous return was detected in three patients with computed tomography angiography. CONCLUSION: Fat component and early venous return are important for a correct diagnosis of hepatic angiomyolipoma. Unfortunately, apparent diffusion coefficient values in hepatic angiomyolipoma were overlapping with those in other benign and malignant tumors. Springer Berlin Heidelberg 2015-04-24 /pmc/articles/PMC4560139/ /pubmed/26366342 http://dx.doi.org/10.1186/s40792-015-0038-0 Text en © Kuramoto et al. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. |
spellingShingle | Case Report Kuramoto, Kunitaka Beppu, Toru Namimoto, Tomohiro Hayashi, Hiromitsu Imai, Katsunori Nitta, Hidetoshi Hashimoto, Daisuke Chikamoto, Akira Ishiko, Takatoshi Iyama, Ken-Ichi Ikeda, Osamu Yamashita, Yasuyuki Baba, Hideo Hepatic angiomyolipoma with special attention to radiologic imaging |
title | Hepatic angiomyolipoma with special attention to radiologic imaging |
title_full | Hepatic angiomyolipoma with special attention to radiologic imaging |
title_fullStr | Hepatic angiomyolipoma with special attention to radiologic imaging |
title_full_unstemmed | Hepatic angiomyolipoma with special attention to radiologic imaging |
title_short | Hepatic angiomyolipoma with special attention to radiologic imaging |
title_sort | hepatic angiomyolipoma with special attention to radiologic imaging |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560139/ https://www.ncbi.nlm.nih.gov/pubmed/26366342 http://dx.doi.org/10.1186/s40792-015-0038-0 |
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