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Discovery of small molecule inhibitors of xyloglucan endotransglucosylase (XET) activity by high-throughput screening

Small molecules (xenobiotics) that inhibit cell-wall-localised enzymes are valuable for elucidating the enzymes’ biological roles. We applied a high-throughput fluorescent dot-blot screen to search for inhibitors of Petroselinum xyloglucan endotransglucosylase (XET) activity in vitro. Of 4216 xenobi...

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Detalles Bibliográficos
Autores principales:	Chormova, Dimitra, Franková, Lenka, Defries, Andrew, Cutler, Sean R., Fry, Stephen C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560162/ https://www.ncbi.nlm.nih.gov/pubmed/26093490 http://dx.doi.org/10.1016/j.phytochem.2015.06.016

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