A Grave Outcome of Posterior Reversible Encephalopathy Syndrome in a Patient Receiving Avastin (Bevacizumab) for Metastatic High-Grade Serous Ovarian Cancer

A 45-year-old female developed neurological symptoms and elevated diastolic blood pressure while on bevacizumab (Avastin) and gemcitabine for recurrent carboplatin-resistant high-grade serous ovarian cancer. A brain MRI diagnosed our patient with posterior reversible encephalopathy syndrome. We are...

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Autores principales: Elmalik, Hind H., ElAzzazy, Shereen, Salem, Khaled S., Bujassoum, Salha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2015
Materias:
Published online: July, 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560300/
https://www.ncbi.nlm.nih.gov/pubmed/26351436
http://dx.doi.org/10.1159/000435805
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author Elmalik, Hind H.
ElAzzazy, Shereen
Salem, Khaled S.
Bujassoum, Salha
author_facet Elmalik, Hind H.
ElAzzazy, Shereen
Salem, Khaled S.
Bujassoum, Salha
author_sort Elmalik, Hind H.
collection PubMed
description A 45-year-old female developed neurological symptoms and elevated diastolic blood pressure while on bevacizumab (Avastin) and gemcitabine for recurrent carboplatin-resistant high-grade serous ovarian cancer. A brain MRI diagnosed our patient with posterior reversible encephalopathy syndrome. We are discussing her presenting symptoms in this paper as well as the management and the outcome. We emphasize the importance of keeping this rare but very serious complication in all patients receiving bevacizumab.
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spelling pubmed-45603002015-09-08 A Grave Outcome of Posterior Reversible Encephalopathy Syndrome in a Patient Receiving Avastin (Bevacizumab) for Metastatic High-Grade Serous Ovarian Cancer Elmalik, Hind H. ElAzzazy, Shereen Salem, Khaled S. Bujassoum, Salha Case Rep Oncol Published online: July, 2015 A 45-year-old female developed neurological symptoms and elevated diastolic blood pressure while on bevacizumab (Avastin) and gemcitabine for recurrent carboplatin-resistant high-grade serous ovarian cancer. A brain MRI diagnosed our patient with posterior reversible encephalopathy syndrome. We are discussing her presenting symptoms in this paper as well as the management and the outcome. We emphasize the importance of keeping this rare but very serious complication in all patients receiving bevacizumab. S. Karger AG 2015-07-16 /pmc/articles/PMC4560300/ /pubmed/26351436 http://dx.doi.org/10.1159/000435805 Text en Copyright © 2015 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article licensed under the terms of the Creative Commons Attribution-NonCommercial 3.0 Unported license (CC BY-NC) (www.karger.com/OA-license), applicable to the online version of the article only. Distribution permitted for non-commercial purposes only.
spellingShingle Published online: July, 2015
Elmalik, Hind H.
ElAzzazy, Shereen
Salem, Khaled S.
Bujassoum, Salha
A Grave Outcome of Posterior Reversible Encephalopathy Syndrome in a Patient Receiving Avastin (Bevacizumab) for Metastatic High-Grade Serous Ovarian Cancer
title A Grave Outcome of Posterior Reversible Encephalopathy Syndrome in a Patient Receiving Avastin (Bevacizumab) for Metastatic High-Grade Serous Ovarian Cancer
title_full A Grave Outcome of Posterior Reversible Encephalopathy Syndrome in a Patient Receiving Avastin (Bevacizumab) for Metastatic High-Grade Serous Ovarian Cancer
title_fullStr A Grave Outcome of Posterior Reversible Encephalopathy Syndrome in a Patient Receiving Avastin (Bevacizumab) for Metastatic High-Grade Serous Ovarian Cancer
title_full_unstemmed A Grave Outcome of Posterior Reversible Encephalopathy Syndrome in a Patient Receiving Avastin (Bevacizumab) for Metastatic High-Grade Serous Ovarian Cancer
title_short A Grave Outcome of Posterior Reversible Encephalopathy Syndrome in a Patient Receiving Avastin (Bevacizumab) for Metastatic High-Grade Serous Ovarian Cancer
title_sort grave outcome of posterior reversible encephalopathy syndrome in a patient receiving avastin (bevacizumab) for metastatic high-grade serous ovarian cancer
topic Published online: July, 2015
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560300/
https://www.ncbi.nlm.nih.gov/pubmed/26351436
http://dx.doi.org/10.1159/000435805
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