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Mycobacterium chelonae Is an Ubiquitous Atypical Mycobacterium

The type of cutaneous infection varies mainly according to the patient's immune status, and the disseminated form is mostly found in the context of immunosuppression. We report the case of a 62-year-old male who was under long-term systemic corticosteroid therapy and presented with a 7-month hi...

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Autores principales: Pinto-Gouveia, Miguel, Gameiro, Ana, Ramos, Leonor, Cardoso, José Carlos, Brites, Maria Manuel, Tellechea, Óscar, Figueiredo, Américo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560325/
https://www.ncbi.nlm.nih.gov/pubmed/26351432
http://dx.doi.org/10.1159/000438898
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author Pinto-Gouveia, Miguel
Gameiro, Ana
Ramos, Leonor
Cardoso, José Carlos
Brites, Maria Manuel
Tellechea, Óscar
Figueiredo, Américo
author_facet Pinto-Gouveia, Miguel
Gameiro, Ana
Ramos, Leonor
Cardoso, José Carlos
Brites, Maria Manuel
Tellechea, Óscar
Figueiredo, Américo
author_sort Pinto-Gouveia, Miguel
collection PubMed
description The type of cutaneous infection varies mainly according to the patient's immune status, and the disseminated form is mostly found in the context of immunosuppression. We report the case of a 62-year-old male who was under long-term systemic corticosteroid therapy and presented with a 7-month history of multiple painless cutaneous lesions at various stages of development: papules, nodules, pustules and hemorrhagic crusts, as well as small erosions and ulcers distributed over the limbs and scalp. Cutaneous biopsy showed a suppurative granulomatous infiltrate with abscess formation. Fite stain revealed numerous extracellular bacilli, suggesting mycobacterial infection, particularly by atypical mycobacteria. Culture of a skin sample revealed Mycobacterium chelonae. The patient started multidrug therapy and showed clinical improvement despite of resistance to one of the antibiotics. This striking presentation underlines the role of immunosuppression with corticotherapy as a major risk factor for these infections. Multidrug therapy is advised and antibiogram is essential in directing treatment.
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spelling pubmed-45603252015-09-08 Mycobacterium chelonae Is an Ubiquitous Atypical Mycobacterium Pinto-Gouveia, Miguel Gameiro, Ana Ramos, Leonor Cardoso, José Carlos Brites, Maria Manuel Tellechea, Óscar Figueiredo, Américo Case Rep Dermatol Published online: August, 2015 The type of cutaneous infection varies mainly according to the patient's immune status, and the disseminated form is mostly found in the context of immunosuppression. We report the case of a 62-year-old male who was under long-term systemic corticosteroid therapy and presented with a 7-month history of multiple painless cutaneous lesions at various stages of development: papules, nodules, pustules and hemorrhagic crusts, as well as small erosions and ulcers distributed over the limbs and scalp. Cutaneous biopsy showed a suppurative granulomatous infiltrate with abscess formation. Fite stain revealed numerous extracellular bacilli, suggesting mycobacterial infection, particularly by atypical mycobacteria. Culture of a skin sample revealed Mycobacterium chelonae. The patient started multidrug therapy and showed clinical improvement despite of resistance to one of the antibiotics. This striking presentation underlines the role of immunosuppression with corticotherapy as a major risk factor for these infections. Multidrug therapy is advised and antibiogram is essential in directing treatment. S. Karger AG 2015-08-12 /pmc/articles/PMC4560325/ /pubmed/26351432 http://dx.doi.org/10.1159/000438898 Text en Copyright © 2015 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Published online: August, 2015
Pinto-Gouveia, Miguel
Gameiro, Ana
Ramos, Leonor
Cardoso, José Carlos
Brites, Maria Manuel
Tellechea, Óscar
Figueiredo, Américo
Mycobacterium chelonae Is an Ubiquitous Atypical Mycobacterium
title Mycobacterium chelonae Is an Ubiquitous Atypical Mycobacterium
title_full Mycobacterium chelonae Is an Ubiquitous Atypical Mycobacterium
title_fullStr Mycobacterium chelonae Is an Ubiquitous Atypical Mycobacterium
title_full_unstemmed Mycobacterium chelonae Is an Ubiquitous Atypical Mycobacterium
title_short Mycobacterium chelonae Is an Ubiquitous Atypical Mycobacterium
title_sort mycobacterium chelonae is an ubiquitous atypical mycobacterium
topic Published online: August, 2015
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560325/
https://www.ncbi.nlm.nih.gov/pubmed/26351432
http://dx.doi.org/10.1159/000438898
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