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Mycobacterium chelonae Is an Ubiquitous Atypical Mycobacterium
The type of cutaneous infection varies mainly according to the patient's immune status, and the disseminated form is mostly found in the context of immunosuppression. We report the case of a 62-year-old male who was under long-term systemic corticosteroid therapy and presented with a 7-month hi...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560325/ https://www.ncbi.nlm.nih.gov/pubmed/26351432 http://dx.doi.org/10.1159/000438898 |
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author | Pinto-Gouveia, Miguel Gameiro, Ana Ramos, Leonor Cardoso, José Carlos Brites, Maria Manuel Tellechea, Óscar Figueiredo, Américo |
author_facet | Pinto-Gouveia, Miguel Gameiro, Ana Ramos, Leonor Cardoso, José Carlos Brites, Maria Manuel Tellechea, Óscar Figueiredo, Américo |
author_sort | Pinto-Gouveia, Miguel |
collection | PubMed |
description | The type of cutaneous infection varies mainly according to the patient's immune status, and the disseminated form is mostly found in the context of immunosuppression. We report the case of a 62-year-old male who was under long-term systemic corticosteroid therapy and presented with a 7-month history of multiple painless cutaneous lesions at various stages of development: papules, nodules, pustules and hemorrhagic crusts, as well as small erosions and ulcers distributed over the limbs and scalp. Cutaneous biopsy showed a suppurative granulomatous infiltrate with abscess formation. Fite stain revealed numerous extracellular bacilli, suggesting mycobacterial infection, particularly by atypical mycobacteria. Culture of a skin sample revealed Mycobacterium chelonae. The patient started multidrug therapy and showed clinical improvement despite of resistance to one of the antibiotics. This striking presentation underlines the role of immunosuppression with corticotherapy as a major risk factor for these infections. Multidrug therapy is advised and antibiogram is essential in directing treatment. |
format | Online Article Text |
id | pubmed-4560325 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-45603252015-09-08 Mycobacterium chelonae Is an Ubiquitous Atypical Mycobacterium Pinto-Gouveia, Miguel Gameiro, Ana Ramos, Leonor Cardoso, José Carlos Brites, Maria Manuel Tellechea, Óscar Figueiredo, Américo Case Rep Dermatol Published online: August, 2015 The type of cutaneous infection varies mainly according to the patient's immune status, and the disseminated form is mostly found in the context of immunosuppression. We report the case of a 62-year-old male who was under long-term systemic corticosteroid therapy and presented with a 7-month history of multiple painless cutaneous lesions at various stages of development: papules, nodules, pustules and hemorrhagic crusts, as well as small erosions and ulcers distributed over the limbs and scalp. Cutaneous biopsy showed a suppurative granulomatous infiltrate with abscess formation. Fite stain revealed numerous extracellular bacilli, suggesting mycobacterial infection, particularly by atypical mycobacteria. Culture of a skin sample revealed Mycobacterium chelonae. The patient started multidrug therapy and showed clinical improvement despite of resistance to one of the antibiotics. This striking presentation underlines the role of immunosuppression with corticotherapy as a major risk factor for these infections. Multidrug therapy is advised and antibiogram is essential in directing treatment. S. Karger AG 2015-08-12 /pmc/articles/PMC4560325/ /pubmed/26351432 http://dx.doi.org/10.1159/000438898 Text en Copyright © 2015 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission. |
spellingShingle | Published online: August, 2015 Pinto-Gouveia, Miguel Gameiro, Ana Ramos, Leonor Cardoso, José Carlos Brites, Maria Manuel Tellechea, Óscar Figueiredo, Américo Mycobacterium chelonae Is an Ubiquitous Atypical Mycobacterium |
title | Mycobacterium chelonae Is an Ubiquitous Atypical Mycobacterium |
title_full | Mycobacterium chelonae Is an Ubiquitous Atypical Mycobacterium |
title_fullStr | Mycobacterium chelonae Is an Ubiquitous Atypical Mycobacterium |
title_full_unstemmed | Mycobacterium chelonae Is an Ubiquitous Atypical Mycobacterium |
title_short | Mycobacterium chelonae Is an Ubiquitous Atypical Mycobacterium |
title_sort | mycobacterium chelonae is an ubiquitous atypical mycobacterium |
topic | Published online: August, 2015 |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560325/ https://www.ncbi.nlm.nih.gov/pubmed/26351432 http://dx.doi.org/10.1159/000438898 |
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