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Sense and Antisense DMPK RNA Foci Accumulate in DM1 Tissues during Development

Myotonic dystrophy type 1 (DM1) is caused by an unstable expanded CTG repeat located within the DMPK gene 3’UTR. The nature, severity and age at onset of DM1 symptoms are very variable in patients. Different forms of the disease are described, among which the congenital form (CDM) is the most severe...

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Detalles Bibliográficos
Autores principales:	Michel, Lise, Huguet-Lachon, Aline, Gourdon, Geneviève
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560382/ https://www.ncbi.nlm.nih.gov/pubmed/26339785 http://dx.doi.org/10.1371/journal.pone.0137620

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