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Validation of the 2(nd) Generation Proteasome Inhibitor Oprozomib for Local Therapy of Pulmonary Fibrosis
Proteasome inhibition has been shown to prevent development of fibrosis in several organs including the lung. However, effects of proteasome inhibitors on lung fibrosis are controversial and cytotoxic side effects of the overall inhibition of proteasomal protein degradation cannot be excluded. There...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4560391/ https://www.ncbi.nlm.nih.gov/pubmed/26340365 http://dx.doi.org/10.1371/journal.pone.0136188 |